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Q:   WHAT IS SICKLE CELL DISEASE?

TYSK
(Things You Should Know)

On this page you'll find a compilation of the most commonly asked questions and answers about Sickle Cell Disease, 

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How long can a sickle cell patient live?

Recent data suggests that the average lifespan of people with Sickle Cell Disease has improved. However, when looking specifically at individuals with public insurance, researchers have found that the average life expectancy is around 52.6 years. It's important to note that male life expectancy at birth is lower, at around 49.3 years, compared to females, who have a life expectancy of around 55 years.

Is there a cure for sickle cell disease?

Yes, there is a way to cure sickle cell disease. The only cure is through stem cell or bone marrow transplants. However, these treatments are not commonly done because they come with significant risks. Stem cells are special cells that are made in the bone marrow, which is a soft tissue found inside some bones.

Does sickle cell only affect Black people?

It's not true that only Black people have Sickle Cell disease. Sickle Cell trait is a blood disorder that can affect anyone, not just Blacks. In fact, it affects around 1 to 3 million Americans and about 8 to 10 percent of African Americans. It's important to know that Sickle Cell trait can also be found in Hispanics, South Asians, Caucasians from southern Europe, and people from Middle Eastern countries.

What are the common symptoms and complications of Sickle Cell Disease?

The most common symptoms include episodes of severe pain, known as "crises," which can occur in various parts of the body. Other symptoms may include fatigue, shortness of breath, delayed growth and development in children, and frequent infections.

In addition to these symptoms, Sickle Cell Disease can lead to various complications affecting different organs and systems in the body. These complications can include damage to organs such as the spleen, liver, and kidneys, as well as increased vulnerability to infections. The abnormal shape of sickle cells can cause blockages in blood vessels, leading to reduced blood flow and oxygen supply to tissues and organs. This can result in organ damage, such as strokes, acute chest syndrome (a condition similar to pneumonia), and leg ulcers. Sickle Cell Disease can also affect the eyes, bones, and joints, leading to vision problems, bone and joint pain, and an increased risk of developing arthritis.

How does sickle cell affect a person's life?

Sickle cell disease can cause problems in many important parts of the body. It affects organs like the heart, liver, kidneys, gallbladder, bones, eyes, and joints. The sickle cells don't work properly and have trouble flowing through the tiny blood vessels, which can lead to damage in these organs.

Is there anything a sickle cell patient should avoid?

Yes, if you have sickle cell disease, it's important to avoid doing very strenuous exercise. It's better to stay active, but be cautious. Avoid activities that make you really out of breath. Additionally, it's best to avoid alcohol and smoking. Alcohol can make you dehydrated, and smoking can lead to a serious lung problem called acute chest syndrome.

What happens if Sickle Cell Disease is left untreated?

Sickled cells can clog the blood vessels that bring blood to our bones. When this happens, the bone doesn't get enough oxygen and can die, which is called avascular necrosis (AVN). If the bone doesn't receive enough blood, the joint can become narrower and the bone may collapse.

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